# CDISC domains PP and SUPPP

**URL:** <https://forum.certara.com/t/cdisc-domains-pp-and-suppp/3458>\
**Category:** Phoenix WNL basics\
**Created:** [December 6, 2019, 3:43pm UTC](https://forum.certara.com/t/cdisc-domains-pp-and-suppp/3458 "2019-12-06T15:43:08Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![spic](https://avatars.discourse-cdn.com/v4/letter/s/ea5d25/32.png) [@spic](https://forum.certara.com/u/spic)\
**Post date:** [December 6, 2019, 3:43pm UTC](https://forum.certara.com/t/cdisc-domains-pp-and-suppp/3458/1 "2019-12-06T15:43:08Z")

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We would like to submit PP domains as part of the pharmacokinetic (PK) deliverable for regulatory submissions for a NCA analysis.

We have seen in the SDTM and SEND implementation guide that it’s recommended to report _“information pertaining to all parameters (e.g. number of exponents, model weighting) should be submitted in either SUPPPP dataset or define”._

Do any of them do this for SDTM/SEND PK datasets and if so what parameters they indicate in SUPPPP ? Do you use PK submit for that ?

Thanks for your help,

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**Author:** ![SimonDavis](https://avatars.discourse-cdn.com/v4/letter/s/d9b06d/32.png) [@SimonDavis](https://forum.certara.com/u/SimonDavis)\
**Post date:** [December 16, 2019, 3:53pm UTC](https://forum.certara.com/t/cdisc-domains-pp-and-suppp/3458/2 "2019-12-16T15:53:11Z")

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We cannot speak for our users as to how commonly this is done in practice. However If you do need to submit this information, then you could create a new variable name and new variable label and build a SUPPPP domain.

(for others following this thread, the SUPP—domain’s main use is to include any non-standard (SDTM) variables.

Example: in SDTM, PP domain does not have an exclusion variable “PPEXCLFL”, but users sometimes need to exclude a “PP” value from descriptive stats but would still like to report it in the PP domain, in this case you would build a SUPPPP domain as shows in the screen below:

STUDYID : STUDYID

RDOMAIN : “PP”

USUBJID : SUBJID

IDVAR : “PPSEQ”

IDVARVAL : PP.PPSEQ (of the appropriate parameter)

QNAM : **“PPWGHT”**

QLABEL : **“Weighting for lambdaz”**

QVAL : “Uniform weighting”

QORIG : QEVAL

Simon

 ![SUPP_PP.png](https://us1.discourse-cdn.com/certara/original/1X/5ce3e1c0815ad50f3a5a93668d9013ca2341da28.png)