# How to include multi-dose in Phoenix model **URL:** \ **Category:** Modelling and Simulation\ **Created:** [July 27, 2018, 8:08am UTC](https://forum.certara.com/t/how-to-include-multi-dose-in-phoenix-model/3341 "2018-07-27T08:08:01Z")\ **Posts on this page:** 2\ **Page:** 1
**Author:** ![wuliang](https://avatars.discourse-cdn.com/v4/letter/w/f6c823/32.png) [@wuliang](https://forum.certara.com/u/wuliang)\ **Post date:** [July 27, 2018, 8:08am UTC](https://forum.certara.com/t/how-to-include-multi-dose-in-phoenix-model/3341/1 "2018-07-27T08:08:01Z")
Dear All, I am working on an PopPK model with Phoenix NLME 8.0，the data were multi-dose design lasted for 3 days (Bid) and collected after the last dose, with timepoints: -0.5h, 0h, 0.5h, 1h, …and I found from the modeling results that the data collected at -0.5h were not included during the Phoenix modeling process, even I added the dosing infos in the original dataset (AMT column) or using SS options, but if using PK model, the -0.5h timepoints could be taken into account during model fitting. I would like to know how to incorparate these -0.5h collected data into modeling in Phoenix Model/NLME? Many Thanks! [Data.xls](https://forum.certara.com/uploads/short-url/c2TSN3U3BtsEEgiBZvY1c6dUe3I.xls) (21 KB) ![Phoenix Model.JPG](https://us1.discourse-cdn.com/certara/original/2X/c/c351c3c4a7d05e57a2f845ade618afb687182b47.jpeg) ![PK Model.JPG](https://us1.discourse-cdn.com/certara/original/1X/8da55806086e83ba6dfe2b46f805a75d6cc89a07.jpeg) ![SS Setting.JPG](https://us1.discourse-cdn.com/certara/original/2X/b/b51db1acb0881142a95ed04e62542abc1f17746f.jpeg) ---
**Author:** ![SimonDavis](https://avatars.discourse-cdn.com/v4/letter/s/d9b06d/32.png) [@SimonDavis](https://forum.certara.com/u/SimonDavis)\ **Post date:** [July 29, 2018, 4:13am UTC](https://forum.certara.com/t/how-to-include-multi-dose-in-phoenix-model/3341/2 "2018-07-29T04:13:10Z")
Could you perhaps attach your project as that would make review of your dose set up etc in the model easier?