# PK 2 Compartment Mixed Absorption Multiple Dose

**URL:** <https://forum.certara.com/t/pk-2-compartment-mixed-absorption-multiple-dose/3251>\
**Category:** NLME-NONMEM model comparisons\
**Created:** [December 16, 2017, 5:06pm UTC](https://forum.certara.com/t/pk-2-compartment-mixed-absorption-multiple-dose/3251 "2017-12-16T17:06:46Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![bwendt](https://avatars.discourse-cdn.com/v4/letter/b/f4b2a3/32.png) [@bwendt](https://forum.certara.com/u/bwendt)\
**Post date:** [December 16, 2017, 5:06pm UTC](https://forum.certara.com/t/pk-2-compartment-mixed-absorption-multiple-dose/3251/1 "2017-12-16T17:06:46Z")

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This is a PK 2 compartment oral model with mixed absorption and multiple doses.

For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.

[NONMEM\_NLME\_TRANSLATION\_PK 2 Comp MixedAbsorption\_MultipleDose.pdf](https://forum.certara.com/uploads/short-url/9s3K7aOlpcBB5MX2kdkqxmRzThC.pdf) (1.53 MB)

[2c\_mixabs.phxproj](https://forum.certara.com/uploads/short-url/kaneXyMVLIHyCC6RZhqJz5QgANu.phxproj) (1.34 MB)

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**Author:** ![shekhar.udct](https://avatars.discourse-cdn.com/v4/letter/s/a5b964/32.png) [@shekhar.udct](https://forum.certara.com/u/shekhar.udct)\
**Post date:** [May 14, 2018, 12:17pm UTC](https://forum.certara.com/t/pk-2-compartment-mixed-absorption-multiple-dose/3251/2 "2018-05-14T12:17:56Z")

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Can Anybody share the phoenix file of this project which can be opened in phoenix 6.4.

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**Author:** ![SimonDavis](https://avatars.discourse-cdn.com/v4/letter/s/d9b06d/32.png) [@SimonDavis](https://forum.certara.com/u/SimonDavis)\
**Post date:** [May 14, 2018, 4:12pm UTC](https://forum.certara.com/t/pk-2-compartment-mixed-absorption-multiple-dose/3251/3 "2018-05-14T16:12:19Z")

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I don’t currently have access to v6.4; it’s no longer officially supported. Follow this thread to learn more about Phoenix 8.1 soming next month [https://support.certara.com/forums/topic/1100-phoenix-8-is-launching-on-october-3-2017/?p=5246](https://support.certara.com/forums/topic/1100-phoenix-8-is-launching-on-october-3-2017/?p=5246)

However the code is discussed in the PDF, but here is the NLME code and also the raw data as a CSV.

Simon.

[2c\_mixabs.csv](https://forum.certara.com/uploads/short-url/nXCtYG8hKKDxu2J8jWJ6FoGPKa2.csv) (59.4 KB)[2c\_mixabs.txt](https://forum.certara.com/uploads/short-url/4hcZPpOLRfG40nOCGaaM8VLqDZS.txt) (2.01 KB)

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**Author:** ![shekhar.udct](https://avatars.discourse-cdn.com/v4/letter/s/a5b964/32.png) [@shekhar.udct](https://forum.certara.com/u/shekhar.udct)\
**Post date:** [June 4, 2018, 9:38am UTC](https://forum.certara.com/t/pk-2-compartment-mixed-absorption-multiple-dose/3251/4 "2018-06-04T09:38:03Z")

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Thank you very much Simon..This really helps..

> [@sdavis](#):
>
> I don’t currently have access to v6.4; it’s no longer officially supported. Follow this thread to learn more about Phoenix 8.1 soming next month [https://support.certara.com/forums/topic/1100-phoenix-8-is-launching-on-october-3-2017/?p=5246](https://support.certara.com/forums/topic/1100-phoenix-8-is-launching-on-october-3-2017/?p=5246)
> 
> However the code is discussed in the PDF, but here is the NLME code and also the raw data as a CSV.
> 
> Simon.

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**Author:** ![llli](https://avatars.discourse-cdn.com/v4/letter/l/b9bd4f/32.png) [@llli](https://forum.certara.com/u/llli)\
**Post date:** [February 27, 2019, 8:37pm UTC](https://forum.certara.com/t/pk-2-compartment-mixed-absorption-multiple-dose/3251/5 "2019-02-27T20:37:19Z")

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Hi Simon,

Would you please also post the data set for NONMEM? It was not included in the phxproj file.

Thanks,

LLLi