# TX Domain Warning: "Invalid value for TXVAL for TRTDOS" when TRTDOS = 0

**URL:** <https://forum.certara.com/t/tx-domain-warning-invalid-value-for-txval-for-trtdos-when-trtdos-0/2055>\
**Category:** SEND\
**Created:** [August 28, 2024, 1:17pm UTC](https://forum.certara.com/t/tx-domain-warning-invalid-value-for-txval-for-trtdos-when-trtdos-0/2055 "2024-08-28T13:17:55Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Sergiy](https://sea1.discourse-cdn.com/certara/user_avatar/forum.certara.com/sergiy/32/2553_2.png) [@Sergiy](https://forum.certara.com/u/Sergiy)\
**Post date:** [February 7, 2025, 7:59pm UTC](https://forum.certara.com/t/tx-domain-warning-invalid-value-for-txval-for-trtdos-when-trtdos-0/2055/1 "2025-02-07T19:59:39Z")

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Hi Adam,

This rule was updated just after release of 2304.3 engine. New upcoming Community engine 2405.2 will not report “0” value as an issue.

Sorry for inconvenience.

Kind Regards,  
Sergiy

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<div class="post-metadata">

**Author:** ![system](https://sea1.discourse-cdn.com/certara/user_avatar/forum.certara.com/system/32/17_2.png) [@system](https://forum.certara.com/u/system)\
**Post date:** [August 28, 2024, 1:17pm UTC](https://forum.certara.com/t/tx-domain-warning-invalid-value-for-txval-for-trtdos-when-trtdos-0/2055/2 "2024-08-28T13:17:55Z")

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While validating SEND Datasets with Pinnacle 21 Community v4.1.0 and FDA Engine 2304.3, there is a warning for “Invalid value for TXVAL for TRTDOS” (SE2366) that is triggered by a TRTDOS value of “0” for our control group SET. This has been our practice to use “0” to represent the treatment dose for the control group and has not given a warning before. We consider “0” numerical which falls within the confines of the rule. Is there any reason this is being flagged by Pinnacle now?