All At the European PKS User Meeting in Paris, users have suggested the inclusion of a business rule based on lamba z fit parameters, in the same way that the AUC Extrapolation rule currently exists. Should this be put forward as a formal requirment for AutoPilot V3 ? Clive
Hi Clive thanks for posting this comment, I think we will try to collate the user comments/requests from this session and circulate as a whole for review but in the mean time it’s probably a good place to capture comments and suggestions. There is an existing related issue; QC_AP_456, which we could perhaps refine. I think the general impression this morning was that users were interested in flagging/masking Lz dependent parameters when adjusted R-squared was less than some admin/user specified value e.g. 0.85. Much like we currently do with AUCinf%extrap. I think the QC_AP_456 I refer to above is looking to qualify this by an additional check I have come across with various analysis protocols. in the past. Flag lambda_z dependent estimates if thalf is not estimated over at least X half-lives where X is typically between 2 and 3 and would be set by the admin/user at run time. Simon.