Hi all,
Can anybody help in obtaining a best fit to the data. The compound follows non-linear PK.
with best regards,
R
Plasma PK Modeling_Nonlinear.phxproj (1.32 MB)
Hi Raghav, I looked at your project and it seemed that you just had to refine your initial estimates and then you need to assess your model. I have done this for you, of the models I tried i believe 2 com with multiplicative error is best on balance; if you look at the model comparer you can se i thas the lowest AIC and generally the best residual plots. To learn more about model fitting and selection why not take one of our online courses e.g.;
http://www.certarauniversity.com/lms/index.php?r=course/details&id=26
Simon.
Plasma PK Modeling_Nonlinear_v64.phxproj (3.52 MB)