parentheses error message

Phoenix Certara Forums Modelling and Simulation
1

Hi, Can you help resolve a parentheses error message in lines 5 and 6? The lines are: deriv(A2 = (Cl2up * C) – (Cl2eff * C2) - (CLpbmc * C2)) deriv(A3 = (Cl3up * C) – (Cl3eff * C3) - (CLpmn * C3)) The full code if helpful is: test(){ #differential equations deriv(Aa = - (Aa * Ka)) deriv(A1 = - (Cl * C) + (Aa * Ka)- (Cl2up * C) + (Cl2eff * C2)- (Cl3up * C) + (Cl3eff * C3)) deriv(A2 = (Cl2up * C) – (Cl2eff * C2) - (CLpbmc * C2)) deriv(A3 = (Cl3up * C) – (Cl3eff * C3) - (CLpmn * C3)) #elimination urinecpt(A1 = (Cl * C)) urinecpt(A2 = (CLpbmc * C2)) urinecpt(A3 = (CLpmn * C3)) #dose dosepoint(Aa, tlag = (Tlag)) #concentrations in compartments C1 = A1 / V1 C2 = A2 / V2 C3 = A3 / V3 Cblood = (C1A) + (C2B) + (C3*C) #residual error error(CEpsblood=1) observe(Cobsblood = Cblood * (1 + CEpsblood)) error(CEps2 = 1) observe(CObs2 = C2 * (1 + CEps2)) error(CEps3 = 1) observe(CObs3 = C3 * (1 + CEps3)) #structural parameters stparm(A=tvA) stparm(B=tvB) stparm(C=tvC) stparm(V = tvV) stparm(Cl = tvCl * exp(nCl)) stparm(Ka = tvKa) stparm(V2 = tvV2) stparm(Cl2up = tvCl2up) stparm(Cl2eff = tvCl2eff) stparm(V3 = tvV3) stparm(Cl3up = tvCl3up) stparm(Cl3eff = tvCl3eff) stparm(CLpbmc = tvCLpbmc) stparm(CLpmn = tvCLpmn) stparm(Tlag = tvTlag) #fixed effects fixef(tvV = c(1000, 5000, 10000)) fixef(tvCl = c(1.6, 16, 160)) fixef(tvKa = c(0.5, 5, 10)) fixef(tvV2 = c(0.002, 0.02, 2)) fixef(tvCl2up = c(2, 200, 2000)) fixef(tvCl2eff = c(0.01, 1, 100)) fixef(tvV3 = c(0.002, 0.02, 0.2)) fixef(tvCl3up = c(2, 200, 2000)) fixef(tvCl3eff = c(0.01, 1, 100)) fixef(tvCLpbmc = c(0.03, 0.3, 3)) fixef(tvCLpmn = c(0.03, 0.3, 3)) fixef(tvTlag = c(1, 1.8, 5)) fixef(tvA(freeze)=c(0.05,0.55,5)) fixef(tvB(freeze)=c(0.0005,0.005,0.5)) fixef(tvC(freeze)=c(0.0005,0.005,0.5)) ranef(diag(nCl)) } Thanks, Marioa.png

2

Dear Mario, I couldn’t see anything wrong with your code so I had a Pharsight developer look at your question. Here is his answer: [size=4]This problem is extremely subtle. The text contains what looks like a minus sign, but it is some oddball character that may have come from another app, like Word. The only way you can tell is its color. If I just replace it with a normal minus sign, that syntax error goes away. Normal minus sign is hex code 0x2D, but this one is 0x96.[/size] This refers to lines 4 to 7 Hope this helps, Ana