HI Folks,
Can we develop PK-PD model with binary reponse data in NLME?
If yes, sharing some more information or suggestion or any built template will be appreciated.
Thanks in advance!!
Regards,
Ygs
HI Folks,
Can we develop PK-PD model with binary reponse data in NLME?
If yes, sharing some more information or suggestion or any built template will be appreciated.
Thanks in advance!!
Regards,
Ygs
Hi Ygs, there are some worked examples listed inthe help;
e.g. Three category multinomial model with a covariate
Simon
Hi Yglsla,
there are also a couple of examples in out PML School (NONMEM-NLME Comparisons):
https://support.certara.com/forums/topic/1272-pd-categorical-response/
Bernd
Thank you Simon and Bernd for information and suggestions.
Thanks..
Regards,
Ygs
note that phoenix has lot of flexibility and you have multi, ordinal :
binary 0/1 is a special case of more general 0/1/2,… models
when using multi or ordinal you will have automatic simulation and vpc
you can also write your LL + simulate statement to do whatever you need