problem about predictive check

[crystal]

Dear all

I have a problem about predictive check. I built a pop PK model, after I finished covariates stepwise, I copied the model and run it in “simple” run mode. Then I copied the final model and accepted all fixed and random effect, trying to get the VPC through “Predictive check” run mode, but the result I got was weird, and I could not find the reason.

Does anyone know why?

Thanks in advance.

Crystal

[cradhakr]

Hi Crystal,

Is this for the same model you sent to the support?

Could you send this to our support e-mail with the project file please?

Thanks

Mouli

[SimonDavis]

Looks like Mouli is handling this as case 121478 but I would say a VPC should typically be run with at least 500 replicates and you only have 2 selected in your screen shot above..

[crystal]

@sdavis

Looks like Mouli is handling this as case 121478 but I would say a VPC should typically be run with at least 500 replicates and you only have 2 selected in your screen shot above..

thank you for your help, Simon, I really appreciate that.