Questions about plots CWRES-IVAR and CWRES-TAD

Dear all,
Thanks for your reading!I’m a student who is learning population pharmacokinetic modeling using Phoenix NLME. In my Pop CWRES-IVAR plot and Pop CWRES-TAD plot, there is always no blue and red lines regadless of the residual error using additive, multiplcicative, mix ratio and so on. Why? Does this matter? How can I solve it?
The total sample size was 157 from 38 patients. The blood collection times were mostly at 0, 1.5, 2, 2.5, 3 h, and partly at 0, 1.5h.
Hope for your answers! Grateful!

There are some attaches.

Hi,

Could you please do the following.

  1. double click on the plot >> Plot will open in a new window

  2. check if the settings are enabled (image below)

Thanks

Mouli

Thanks for your help. I have checked as your advice, but the settings do not seem to be a problem?

[quote=“cradhakr, username:cradhakr”]

Hi,

Could you please do the following.

  1. double click on the plot >> Plot will open in a new window

  2. check if the settings are enabled (image below)

Thanks

Mouli

[/quote]

If the loess is changed to linear, there is a blue line. Can this show a satisfactory fitting?

[quote=“cradhakr, username:cradhakr”]

Hi,

Could you please do the following.

  1. double click on the plot >> Plot will open in a new window

  2. check if the settings are enabled (image below)

Thanks

Mouli

[/quote]

Hi could you change the graph from “Linear,” to “Loess.” You will get bothe the red and the blue line.

Thanks

Mouli

Hi Mouli, the attachment is the result if i choose loess (no blue or red lines).