I have a problem about the Stepwise run model. I built a POP PK model, after I finished covariates stepwise, everything seems to be good, but when I check the Results—TextOutput—Stepwise Text, it confuses me that the criterion of stepwise forward turn from 3.841 into 5.991 from cstep010 to cstep015(Add P value=0.05)? Does anyone know why?
• The LRT compares two likelihoods • For nested models the difference of two log likelihoods is asymptotically chi-squared distributed: – For 1 parameter difference (1 degree of freedom) the critical value from the chi-squared distribution is ‘3.84’ (P=0.05) \