I am trying to build a population model with the gamma Delay statement to delay the absorption of the drug. I wrote a PML statement using the knowledge from certara phoenix assistance that described this concept. There is no warning but no iterations when I run the model, and the status is “in progress.” I am not sure if the statement needs a correction. The drug was administered orally, and previous population analysis shows two compartments model best describes its PK.
Can I please get help on this issue?
Thanks, Mouli, for your answer and providing an example project.
I tried to use the same PML statement however both V2 and CL2 were not estimated well. I notice there are no iterations, and both are estimated with very high % CV (% in thousands).
I am wondering if we can use A1 with delay function for an oral drug instead of Aa.
Sorry for the delayed response. Is it possible for you to share your project file? I would recommend not to use the forum. You could e-mail it to support@certara.com or please let me know a suitable time I can connect with you over Teams.