Hello, I am trying to analyze two-way crossover bioequivalence study using Phoenix. How can I test for treatmentgroup interaction? The followinig procedure is used in SAS: PROC GLM data=pk; CLASS SUB PER SEQ TRT GROUP; MODEL LAUC LAUCINF LCMAX = GROUP SEQ SEQGROUP SUB(SEQGROUP) PER(GROUP) TRT TRTGROUP /SS1 SS3; TEST H=SEQ GROUP E=SUB(SEQ*GROUP); ESTIMATE ‘TEST VS REFERENCE’ TREAT 1 2; LSMEANS TREAT/CL PDIFF ALPHA=.10; RUN; I am trying to do the same analysis in Phoenix. Thanks
Hello, The TEST statement in your SAS code is not implement in the current PHX 1.3 release. It has been implemented for the next release, for any fixed effects model, such as the model in your code. Regards, Linda Hughes
Hi Linda, So is there any way to test for treatment-by-group interaction in the current version of Phoenix? Thanks
If treatment by group is a model term (as in your SAS code, TRTGROUP), then the Partial Tests tab in the output has a test for the significance of the treatmentgroup term in the model. For this test, the residual error (measurement noise) is used as the error term or denominator for the test. In other words, the significance of each model term is compared against the significance of the residual error. Regards, Linda Hughes