Hi all,
is it possible to apply weighting shemes when running a Phoenix model? Like the option 1/Yhat or 1/Yhat^2 in the WinNonlin classic platform.
thanks,
Chris
Hi Chris, the simple weighting used in the WNL classic engine to account for residual error is now handled as Eps (epsilon) and to get started you can consider that;
Additive is uniform in classical WinNonlin (Cpred + eps)
Multiplicative is 1/YhatYhat in WNL __(Cpred + Cpredeps)__
Power is (Yhat)-2a (Cpred + Cpreda*eps)
This has been discussed a few times so using the search function could give you some more examples.
e.g. http://www.certara.com/forums/topic/251-weighting-in-phoenix-model/?hl=weighting
and http://www.certara.com/forums/topic/52-model-building-syntax-with-phoenix/?hl=weighting#entry121
among others.
Simon
