Coding a PK/PD Model with a Placebo effect

Phoenix Certara Forums Modelling and Simulation
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Placebo_PD_Model.phxproj (891 KB)

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Nathan: Thank you for presenting this: I look forward to seeing the link reactivated and studying the example.

Angus

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formatting and link to PHXPROJ should be restored now.

Simon

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Nathan,

Thanks for this example!

Would the following form give you a u shape for the placebo? Have you seen examples of placebo models that are not linear as you described?

Eplacebo = Kin*(slopet+slope1t^2+slope2t^3) - KoutEplacebo

Claudia