Dear all,
I am doing the dose proportionality analysis with power model, and I have a question regarding the result interpretation. I know the Smith criterion, in which the 90% CI of β need to fall in the (1+ln0.8/lnr,1+ln1.25/lnr) range. However, this criterion is very strict to most of the studies.
Is there any other widely accepted criterion?
Some people says as long as the 90% CI across 1, it can be concluded as DP. However, I could not see any regulations about this. Is there anyone use this criterion?
Thanks
MDMD