Integration for AUC in PML model

Jason, Many thanks for your help! I understand the 10% difference, now. I have tried both of your suggestions and found the second version to be more appropriate in my case. Thank you Bertold

I would like to derive AUC as a secondary parameter from a pop PK model but the code included in this thread is not recognized in the current NLME build e.g. secondary(AUC = AaDose/tvV/tvKe). Is there anybody out there who can please provide the updated code? Thank you.

If this no longer valid, then it suggests that you have changed one of the built-in models and then it will depend on what changes you made as to what the valid formula would be. If you are in text mode you can simply use;

deriv(AUCx=C)

more options like partial AUCs are described on the forum before e.g. earlier in this actual thread and also here;

https://support.certara.com/forums/topic/371-assistance-calculating-auc-as-secondary-parameter/?p=1639

Simon