IVIVC

Dear All, Can anyone tell how to do IVIVC correlation by using Winnonlin. Plese tell how to enter the data in winnonlin sheet for IVIVC. Thanks & Regards Raja

Raja, as I said on the BEBAC board where you first asked this question; you need to be a little more specific. Example files are given of possible formats in the WinNonlin\Examples folder. e.g. ivivc_diss.pwo, ivivc_vivo.pwo and ivivc_test.pwo. Chapter 8 of the Examples guide, (at least in the 5.2.1 guide), is dedicated to stepping through this project. Then you could set up your files in a similar format, or at least you will understand some of the mapping options available to you. The key thing is to keep formulation names consistent between vitro and vivo data to ensure the program can match up the profiles. Lastly there is actually a Forum for this topic already; Certara | Drug Development Solutions Best regards, Simon. Forthcoming meetings and training -Certara | Drug Development Solutions; Transitioning to Phoenix NLME v6.1: 8 June 2010 Berlin, Germany (prior to PAGE). Transitioning to Phoenix v6.1: 6 Sept 2010, Amsterdam, Holland. Introduction to Phoenix v6.1: 7-9 Sept 2010, Amsterdam, Holland.

Hi Simon! [quote]Lastly there is actually a Forum for this topic already; Certara | Drug Development Solutions For both Sub-Boards of WinNonlin Classic Forum I only get “Access denied!”… :wink:

Hi Simon, link not accessible. Raja

interesting I’m logged in as a normal user and can see it. I’ll start a thread there as a test.

Hi Simon! Very strange. Couldn’t post some months ago as well (see here). Didn’t work couple of hours ago (see below): Now it’s working - did you upgrade me? [color=#FF0000][size=4]BTW, don’t feed the troll…[/size][/color]

Sorry but it appears that a security setting was changed on that specific forum that made it only visible to administrators. We’ve corrected the problem and everyone should be able to access it now. Simon.