Linear Mixed Effects Model Estimates

[littlepetinga]

Hello All,

I am using Phoenix WinNonlin 8.2 Linear Mixed Effects Model tool to identify differences between a Treatment and Placebo.

On the Final Fixed Parameters output, I noticed that the program is calculating the estimate, CI and p-value for Placebo, and that for Treatment those appear as ‘Not estimable’.

I ask if it’s possible to define the variable (e.g., Treatment instead of Placebo) for which the program will calculate the estimates.

Thank you in advance

Sara

[bwendt]

Dear Sara,

in principal, you have an input with a column where you specify your Treatment:

You would then use this column (Treatment) as variable in your model specification:

Please refer to our LinMix example that you find in your Phoenix installation.

Bernd