Q: In NLME core output text there is an entry for LLLaplace but I am not using a Laplacian engine. What does it mean?[color=#FF0000][/color] A: LLLaplace term is simply the raw log-likeihood of the fit. The more positive, the better. It gets a contribution from every observation and from every et[color=#0000FF][/color]a. Enhancement: This is potentially confusing so Pharsight has logged an enhancement (QC 11831) to change this string to “log like” in the future.[color=#00BF00][/color]