This is a PK 1 compartment IV infusion model. For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.
In NLME, the model engine is Quasi-Random Parametric Expectation Maximization (QRPEM)
For details about QRPEM, refer to Phoenix Help > Contents > Phoenix Model > Phoenix Model Run Modes, Engines, and Output > Phoenix Model Engines > QRPEM.
In NONMEM, the model engine is Importance Sampling (IMP) EM.
NONMEM to NLME Translation PK 1comp IV Infusion QRPEM IMP.pdf (721 KB)1Comp_IV_Infusion_QRPEM_IMP.phxproj (1.22 MB)