This is a PK 1 compartment model, with multiple oral dose administrations to steady state (SS). The model is fit using First Order Conditional Estimation (FOCE). For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.
1Comp_Oral_Multiple_Dose_SS.phxproj (1.18 MB)NONMEM to NLME Translation PK 1comp Oral Multiple Dose SS.pdf (1.49 MB)