Hi, Is it possible to use the Phenix IVIVC module if I only provide the in-vitro dissolution and in-vivo absorption dataset for 3 formulations without providing the IV or IR profile? I generated the in-vivo absorption data per subject for three ER formulations by using Wagner Nelson with a literature IR half life. I then averaged the in-vivo data for each ER formulation. I proceeded with the IVIVC module and arrived at the in-vivo data input stage. This is where I got stuck. I clicked “Data already deconvolved and averaged” in the In-vivo data option and two new panels appear → UIR panel and In-Vivo Fit Panel. What am I supposed to provide as input for the UIR Panel? According to the help menu. “In the UIR panel, map a data set that contains the UIR polyexponential parameters in a stacked format. Use the UIR Mappings panel to identify how the UIR data are used in the IVIVC object.” I should provide info for the following columns: 1) InVivo Formulation: drug formulation identifiers. 2) Parameter: IVIVC model parameters for each formulation. 3) Estimate: estimated parameter values. For column 2, should I provide the names of the polyexponential parameters? like V_F, K01, K10, Tlag. For column 3, it will be the values for the polyexponential parameters? I provided data for both UIR and in-vivo fit panels accordingly but the program refused to go to the next stage “Build Correlation” Thanks John