RSE calculation for BSV

Phoenix Certara Forums Pirana and RsNLME
1

Hello,

I do not understand how Pirana calculates RSE for BSV.

In my example :

BSV_CL %CV 58.5 % (38%) [0%]

In the .lst from NONMEM:

final parameter estimate: 3.42E-01

se of estimate: 2.61E-01

I understand the calculation of CV for BSV (using root square of 0.342) but not RSE using these values ?

Thanks in advance

Nathalie

2

Nathalie, are you able to share your project (and ideally the corresponding NM code/lst?)

If you aren’t comfortable sharing here - you can email it to support where it will be treated in strict confidence. Simon.

3

Hi Nathalie,

I hope this link would be useful to you, also the method to calculate RSE in Pirana.

RSE_calculation.png
RSE_calculation.png940×239 52.6 KB

Pirana Assistance (certara.com)

Thanks and regards

Chandramouli (Mouli)

4

Thanks a lot for your answer and the link !

Nathalie