why effect model displays straight lines with some dose groups?

Phoenix Certara Forums Modelling and Simulation
1

Never mind I figure it out. :slight_smile:

Thanks

Jian

2

If it’s something that can help others, please share, Simon.

" I developed PKPD model with multiple dose groups. PK model works well. So I fixed PK parameters and try to fit PD data. However, only data from two groups can be fit on Initial Estimates tag. Model displayed straight line for data of other two dose groups. Don’t know why that happened. "

3

It looks like that something missed when I duplicated PK model. It never happened before. So I just reran the PK model and copied/pasted the text part of code on a PKPD model. Then it works.

Thanks

Jian