Dear All, this seems like such a silly question but I can’t seem to find the answer in any documentation. My input is conc in ng/mL and time is in minutes so I’m getting V in mL and Cl in mL/min. However, I desire the results to be expressed for V in L and for Cl in L/hr. How do I get NLME to do that for the output? Additionally, how do I get units rounded as I desire? Kind regards, Jim happy to be using NLME 1.1
Hi Jim, Phoenix models do not do unit conversations. The way it works is that if your data (time, conc, dose) has units in the header rows, those units will be used to label the output model parameters. In this situation, there is no option to enter units . If the data doesn’t have units then the user can enter the units for each parameter but the user needs to enter the correct unit as it is a simple ‘label’. No conversion will be done. The only way to change units is to use a data>column transformation object on the results or to transform the data input to have the desired units prior to the model run. Rounding is available when tabulating data (Table object - decimals or significant digits) or copying the results to the data folder (right click) and then using the display format. Hope this helps, Ana
Hi Ana, Thanks for this confirmation. I’ll stop searching for a solution. My experience from WNL where we could convert units and determine precision of output lead me to think the same would be true for NLME. Kind regards, Jim
This post is from a long time ago. Is it still true that we can’t convert the output units in NLME? > Are there still no options to change the output units directly? If I want results in a different unit, do I need to change the original raw data units?
can you give a concrete example there is several way to convert the units in your model example divide by volume or manipulate F to convert dose to molar units etc. what exactly do you need ?
This is the output of my NLME run. I would like to change the unit of tvV mgmL/ng to “L” and tvCL mgmL/(ng*h) to “L/h” with automatical conversion of the Estimate values.
what i do is put my dose in as the same units as my conc or vice versa to get my units to consolidate to the simplest units, else you can post process with the Properties feature in a Data Wizard. i.e. in your case if you first converted to be working with mg/L and mg in oyur inputs then you would get your desired units by default. Simon
Great! Thank you for the tip. This is the same as how nonmem works. Have a great weekend!
