Error on Phoenix

General
1

I have been using Phoenix for NCA and PK compartmental modeling and simulation. I have been running into the following error messages saying that “length can’t be less than zero. Parameter name: length”.

This happen when I was simply running NCA from simulated time vs conc values from PK modeling table, or doing simulation of PK when dosing tab had just Aa value and Time of 0, if I add an extra dosing at 24 h for example, it would execute okay without error.

Can you please help? I am not sure what I was doing wrong to fix it.

Thanks,

Chun

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2

Hi Chun Li, i’m not sure from you description, please can you post a project exhibiting this problem here or email it to support@certara.com where it will be treated in confidence, thanks Simon.
PS if you are running NCA post simualtion, then consider requesting the parameters in your initial model e.g. Assistance calculating AUC as secondary parameter - #12 by SimonDavis