Hello I am a beginner, infact a learner of this phoenix environment, and modelling I have my data in NONMEM format in a excel file, which I would like to convert to phoenix format, is thee a way to di it within phoenix before sending the data to NLME Thank you in advance, Sincerely Chakradhara
Chakradhara, If your data file is ready for NONMEM analysis, then it should be possible to analyse in Phoenix NLME as it stands; if not then you can of course use the data tools to restructure your data. I would suggest you build your model in NLME first and then map in your source data; if you look the warnings tab then you will see what else is expected, if you have some propblems still then please just post your project to this thread. Lastly here is an example of mapping the ‘pheno’ dataset from NONMEM to the corresponding model in Phoenix (look in the NLME examples guide (found in C:\Program Files (x86)\Pharsight\Phoenix\docs) for more case studies to practise with; 
Note the column names need not match (or initially exist) in the source data, nor are units required but if you do supply all units (e..g. time, conc & dose) then the output parameters will have units calculated for you. Simon.
Dear Chakradara As long as you have only one response and one route of administration, the NONMEM format will work. However if you have let say 2 responses, NONMEM stacks all the responses in one column with the CMT column as identifier. The NLME format requires each response to be associated with one specific column. You can use the powerful database managemnent tools implemented in PHOENIX to get the required format. You take the NONMEM data and use the split option by CMT. This gives you data for CMT=1 and CMT=2. Then you change the name for response 1 to PK and response 2 to PD for example (in the NONMEM data set, they are all under DV) and use the merge option with dort key id and time. Now if you have let say oral and IV dosing, in NONMEM again all will be under the DOSE column with CMT as identifier. You need then to transofrm the data into the NLME format with one column for IV dose and one column for oral dose. The exact same strategy can be used to do so (split and merge). If you have still difficulty, let em know and I will prepare for you a project that show all the steps. Best Serge PS: Sorry for all typo errors, do we have a spelling check here?
An alternative work around that I found that works very well when dealing with NONMEM like datasets in PHXis to use the data wizard to run a transformation on the data, which saves you from splitting and remerging the dataset. With the data wizard, you can select a custom transformation and use the “if” language to slide all of the observations in a given compartment (CMT) out. Specify a new column name, for example Conc The “if” language will look something like so. if(CMT = 2, DV, ) This will slide all of the observations out in to a new column called “Conc” Don’t forget to assign the radio buttons to your compartment and DV values.
Hi Chakradhara, Few more comments : Phoenix can directly read excel files while nonmem can only handle text files. I do exactly how you described but one thing you should be aware of is that the MDV column will exclude all observation on that line suppose you have Parent Metabolite at the same time and you want only to exclude the parent concentration from the analysis then you will need your data to be on two lines ( this is the case if it is in nonmem format). Also Phoenix is different from Nonmem in the sense it is aware of the missing value an empty cell means missing to need fro mdv to define it as missing. Sometimes we have values but we want to ignore them and that is when mdv is handy. Should you have any other question let me know. Samer