PK 2 Compartment Mixed Absorption Multiple Dose

Phoenix Certara Forums NLME-NONMEM model comparisons
1

This is a PK 2 compartment oral model with mixed absorption and multiple doses.

For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.

NONMEM_NLME_TRANSLATION_PK 2 Comp MixedAbsorption_MultipleDose.pdf (1.53 MB)

2c_mixabs.phxproj (1.34 MB)

2

Can Anybody share the phoenix file of this project which can be opened in phoenix 6.4.

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I don’t currently have access to v6.4; it’s no longer officially supported. Follow this thread to learn more about Phoenix 8.1 soming next month https://support.certara.com/forums/topic/1100-phoenix-8-is-launching-on-october-3-2017/?p=5246

However the code is discussed in the PDF, but here is the NLME code and also the raw data as a CSV.

Simon.

2c_mixabs.csv (59.4 KB)2c_mixabs.txt (2.01 KB)

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Thank you very much Simon..This really helps..

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Hi Simon,

Would you please also post the data set for NONMEM? It was not included in the phxproj file.

Thanks,

LLLi