Hi there! We got the data from our pilot clinical trials: data sets of plasma concentration for 1) IV bolus 1000 mg (female); 2) IR tablets 500 mg (2 times/day, 0-12, 12-24, steady state 14 days, male); 3) CR tablets 1000 mg (once a day, steady state 14 days, male); 4)CR tablets 1000 mg (steady state 5 days, female). The data are very inconsistent (see attachment). Can WNL help me to understand the behavior of our drug? I mean, perhaps I can get any model or any calculations to understand where the active substance is absorbed. Thank you in advance. Best wishes, Helen [file name=Mild_Triz_SS_april2012.phxproj size=846910]/extranet/media/kunena/attachments/legacy/files/Mild_Triz_SS_april2012.phxproj[/file]Mild_Triz_SS_april2012.phxproj (827 KB)
Hi Helen, I saw you were also discussing this on the BEBAC forum; Bioequivalence and Bioavailability Forum • WinNonlin Are you looking for some consulting assistance with your compound ? Simon.