Are their features available in PhoenixNLME to implement a mixture model (based on pharmacodynamic responders and nonresponders) similar to what has been accomplished in NONMEM? Thanks! Lance
Hi, Without more details on what you are trying to do it is hard to provide you a good answer on how to handle the responder/ non-responder PK/PD. Several statistical methods are available. Phoenix NLME does not currently have parametric mixture modeling. On the other hand it has a nonparametric engine that will help you with the detection of subpopulations. Samer